The deleterious effects of a Paleolithic diet appear to undermine the positive effects of a Crossfit-based high-intensity circuit training exercise program.

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I touched on paleo diets before in Paleolithic Lessons ( and I featured a guest blog on the subject: Will The Real Paleo Diet Please Stand Up? (

I wrote a book on low carb diets (now available free full-text online: and touched on it in Atkins Diet: Trouble Keeping It Up ( and Low Carb Diets and Coronary Blood Flow (

And just two months ago, I published a bunch of videos on the low-carb keto diet:

And if you’re thinking, yeah, but what about the size of the cholesterol, small and dense or large and fluffy? Please see my video Does Cholesterol Size Matter? (

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Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM

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26 thoughts on “Flashback Friday: Paleo Diets May Negate Benefits of Exercise

  1. Get the preface for Dr. Greger's brand-new book, How Not to Diet, by subscribing to his free newsletter at: https://bit.ly/NF_newsletter . -NF Team

  2. Paleo is a religion man they don’t care about facts they just wanna eat meat. They’ll call it something new every 10-20 years.

  3. Lostening to Dr. Greger is like a roller coaster ride . Very entertaining. But did he just say a „good cocaine habbit“?? @4:30

  4. Sadly, the Atkin diet advocate isn't convinced by the science. If they find scientific knowledge compelling, they would've never started it, so it kind of too late. They like their temporary weight loss and muscle atrophy. We'll have to wait until a heart attack to change their minds. I've talked to many during lunch hour and don't know what else to tell them.

  5. I wish Dr. G would stop picking one study that casts a negative light on any one diet and then ignore positive ones. I bugs me because it undermines his credibility and makes him an easy target for all of the "he cherry-picks" claims. The way forward seems to be to say this is what the evidence says right now and that's that. It would make the dialogue between omnivores and vegans and plant-based folks much healthier.

    Consider these studies:
    Frassetto, L., Schloetter, M., Mietus-Synder, M., Morris, RC Jr., Sebastian, A. (2009). Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type diet. European Journal of Clinical Nutrition. 63(8):947-55. doi: 10.1038.

    Ryberg, M., Sandberg, S., Melberg, C., Stegle, O., Lindahl, B., Larsson, C., Hauksson, J, Olsson, T. (2013). A Palaeolithic-type diet causes strong tissue-specific effects on ectopic fat deposition in obese postmenopausal women. Journal of Internal Medicine. doi.org/10.1111/joim.12048.

    Lindeberg, S., Jonsson, T., Granfeld, Y., Borgstrand, E., Soffman, J., Sjostrom,K., Ahren, B. (2007). A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. Diabetologia. 50(9):1795-1807. doi: 10.1007/s00125-007-0716-y.

    The Beneficial Effects of a Paleolithic Diet on Type 2 Diabetes and Other Risk Factors for Cardiovascular Disease

    De Menezes, E., Sampaio, H., Carioca, A., Parente, N., Brito, F., Moreira, T., de Souza, A., Arruda, S. (2019). Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis. Nutrition Journal. 18(1):41. doi: 10.1186/s12937-019-0457-z.

    Effects of a Paleolithic Diet on Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  6. LDL is bad?
    Who decided that?
    Paleo diet negates the positive effects of training?
    Who decided that?

    You dont get to decide. Nothing you said in this video is true. Nothing you claimed to be true, applies to me nor anyone I know. You are false.

  7. The paleo diet is a joke. I see paleo meals at my grocery store that always include a big patty of meat. Paleo people might have eaten that way several times a year, but not every night given that they ate 150 grams of fiber a day!

  8. The paleo diet exists just as much as, say the 10th century diet or the sixteenth century diet. It doesn't mean anything. The name should be the ignorant diet.

  9. I must disagree with rising of insulin because of eating meat, my wife is diabetic and she cannot rise his low level of insulin with meat, and often she has to eat "junk" food because insulin response is so slow

  10. The healthy individuals who had a 20 percent rise in LDL would still be in the normal range according to harvard health:
    "Aim for an LDL of 100 or lower, ideally through lifestyle changes such as weight loss, a healthy diet, and exercise, plus cholesterol-lowering statins, if indicated. "

    The others probably shouldn't be working out that strenuously because they are too overweight.

    This is not something to worry about and sounds more like an apples and oranges argument where meat has a slightly different effect on cholesterol, just as carbs tend to raise blood sugar more which is considered bad by some people even when it's in the normal range. It's people making a big deal out of something perfectly normal because it's not their chosen diet.

    If this diet helps them get their bmi to a normal range and it's reasonably balanced, it's good thing, not a bad thing. A carnivore diet, that's an extreme that would have to be considered a temporary weight loss measure.

  11. This is why some keto docs recommend high fat keto- avoid the insulin. But then you have the issue of intramyocellular lipids.

  12. There HAS to be more going on in the body when someone eats a burger compared to pure sugar. It can't be like for like even with the insulin spike.

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